Friday, May 11, 2007
Meet Vinny, he has Canavan Disease one of the most common cerebral degenerative diseases of infancy. His family is hosting a blog with several really cool items for auction, including books, fly fishing gear and hiking clothes. I believe the blog takes bids on the items for sale and takes donations of items to sell.
Paola Leone, Ph.D. and her team are the only researchers in the entire world working directly with Canavan children. Dr. Leone and her team have pioneered a brain gene therapy to halt the progression of the disease. Their research offers a glimpse at treating and eventually eradicating similar degenerative diseases of the brain, such as Parkinson's disease, Alzheimer's disease, Lou Gehrig's disease (ALS), and Multiple Sclerosis.
Dr. Leone and her team are currently at the University of Medicine and Dentistry of New Jersey, in Camden, New Jersey. The brain gene therapy is conducted at Cooper University Hospital. The procedure involves the insertion of six catheters into the brain that deliver a solution containing 600 billion to 900 billion engineered virus particles. The virus, a modified version of AAV, is designed to replace the aspartoacylase enzyme. Children treated with this procedure to date have shown marked improvements, including the growth of myelin with decreased levels of the n-acetyl-aspartate toxin. From Wikipedia
Remarkable resultswhich may help Parkinson's Disease, Cananvan Disease and Alzeimers?